How Quanto reads SCIEX .wiff files and builds MRM methods from the WIFF.

Raw data

Item Notes
File .wiff (and companion files as required by the vendor reader)
Multi-sample Samples inside a WIFF are addressed as #n (sample index)
Extract style MRM-centric — transitions from the WIFF

Reader add-in: SciexWiff using Clearcore2 / SCIEX vendor APIs. Support DLLs live under:

C:\Program Files\Quanto\AddIns\VendorSupportFiles\Sciex\

Method import

Source What you point at What comes in
SCIEX method from data .wiff file MRM compounds / transitions (SciexWiffMethod)

Standalone .msm is not supported with the current minimal SCIEX DLL set — use method-from-WIFF.

Import: Method → Load / Import — Replace or Append (Method design).

Empty or odd chromatograms

  1. Confirm the Quant MRM matches a transition in the WIFF.
  2. Confirm the correct multi-sample #n was added.
  3. Confirm VendorSupportFiles\Sciex is present for this build.

See Troubleshooting.

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